左奕: 博士、研究员、博士生导师

通讯地址：成都市望江路29号四川大学分析测试中心434室

联系方式：028-85418178

E-mail:zoae@scu.edu.cn;zoae@vip.sina.com

教育及工作经历：

2012--至今 博士导师

2011--至今四川大学分析测试中心 研究员

2006--2011四川大学分析测试中心 副研究员

2000--2006 四川大学分析测试中心 硕士、博士     专业：生物医学工程

主要工作业绩：

2003和2006年分别获得四川大学工学硕士和博士学位，2007年在荷兰Nijmegen大学医学中心从事博士后研究（指导教师：J.A. Jansen教授，荷兰皇家科学院院士），现为四川省第九批学术与技术带头人后备人选（2011），四川省科技青年联合会理事，2015年度成都市政府特殊津贴获得者。作为项目负责人承担科技部国家重点研发计划专项课题一项、863重点项目课题和子题项目各一项、国家自然基金面上项目和四川省国际创新合作、四川省科技攻关项目各一项，作为主研人员积极参与国家973项目、国际科技合作与交流项目、国家自然科学基金项目、国家十五科技攻关项目、国家863重点项目等十余项国家级和部省级项目的研究。

目前已申请并授权欧盟发明专利1项，申请中国发明专利35项，授权26项，申请并授权实用新型专利4项，申请PCT专利9项，撰写国家标准2项（已颁布），获教育部科技进步一等奖、省级科技进步二等奖和省自然科学二等奖各一项，成都市人民政府特殊津贴一项，发表第一作者（含通讯作者）57篇。

主要研究领域/方向：

目前主要开展纳米有机/无机复合生物材料研究与产业开发，正从事纳米材料、仿生生物材料和活性生物材料的研发及其制品的评价研究，包括磷灰石晶体取向生长及机制研究；生物活性和电活性高分子及其复合材料的制备及评价；可注射自固化口腔和骨科充填剂研究；超细电纺纤维制备及应用研究；3D打印组织工程支架及表面改性研究；以及降解聚合物载药控释等方向的研究。

研究生招生专业：

生物医学工程、材料学

代表性科研成果：

1. Yi Zuo,Fang Yang, Joop G.C. Wolke,Yubao Li,John A Jansen*, Incorporation of biodegradable electrospun fibers into calcium phosphate cement for bone regeneration, Acta Biomaterialia,2010, 6: 1238-1247

2. Zuo Yi, Li Yubao*, Li Jidong, Zhang Xiang, Liao Hongbing, Wang Yuanyuan, Yang Weihu, Novel Bio-composite of Hydroxyapatite Reinforced Polyamide and Polyethylene: Composition and Properties, Materials ScienceandEngineering A-Structural Materials Properties Microstructureand Processing, 2007, 452-453: 512-517

3. Yi Zuo, Yubao Li*, Jie Wei and Yonggang Yan, Influence of Ethylene Glycol on the Formation of Calcium Phosphate Nanocrystals, Journal of Materials Science & Technology, 2003, Vol. 19, No.6, 628-630

4. Qing Zhao, Jieqiong Chen, Jiajing Tang, Xiaoyu Lei, Jinzheng Zhang, Yinglong Zhang, Jidong Li, Yi Zuo*, and Yubao Li*, Self-activating phosphorus-rich substrate import enzyme catalytic domains for bone regeneration, Advanced Functional Materials, DOI: 10.1002/adfm.202316428, 2024, 2316428

5. Jiajing Tang, Yinglong Zhang, Wei Fang, Yi Man, Jinzheng Zhang, Qing Zhao, Xiaoyu Lei, Jieqiong Chen, Jidong Li, Yubao Li,Yi Zuo*, Electrophysiological microenvironment and site-specific cell behaviors regulated by fibrous aniline trimer-based polyurethanes in bone progressive regeneration,Chemical Engineering Journal, 2023, 460: 141630

5. Yinglong Zhang, Jiajing Tang, Wei Fang, Qing Zhao, Xiaoyu Lei, Jinzheng Zhang, Jieqiong Chen,Yubao Li and Yi Zuo*,Synergetic effect of electrical and topographical cues in aniline trimer-based polyurethane fibrous scaffolds on tissue regeneration,Journal of Functional Biomaterials, 2023, 14, 185

6. Jieqiong Chen, Qing Zhao, Jiajing Tang, Xiaoyu Lei, Jinzheng Zhang, Yuping Li, Jidong Li, Yubao Li* and Yi Zuo*，Enzyme-activated biomimetic vesicles confining mineralization for bone maturation, ACS Applied Materials & Interfaces, 2024, DOI: 10.1021/acsami.4c03978

7. Yiting Sun1#, Yinglong Zhang2#, Yibo Guo1, Dongming He3, Wanlin Xu1, Wei Fang4, Chenping Zhang1, Yi Zuo2*, Zhen Zhang1*, Electrical aligned polyurethane nerve guidance conduit modulates macrophage polarization and facilitates immunoregulatory peripheral nerve regeneration, Journal of Nanobiotechnology, 2024, 22:244

8. Xiaoyu Lei#, Jian Wang#, Jie Chen, Jing Gao, Jinzheng Zhang, Qing Zhao, Jiajing Tang, Wei Fang, Jidong Li, Yubao Li and Yi Zuo*, In vitro evaluation of antibacterial efficacy optimized with cellular apoptosis on multi-functional polyurethane sealers for root canal treatment,Journal of Materials Chemistry B, 2021, Vol. 9, No. 5: 1370-1384

9. Yinglong Zhang, Jiajing Tang, Wei Fang, Qing Zhao, Xiaoyu Lei, Jinzheng Zhang, Jieqiong Chen, Yubao Li and Yi Zuo*, Synergetic effect of electrical and topographical cues in aniline trimer-based polyurethane fibrous scaffolds on tissue regeneration, Journal of Functional Biomaterials, 2023, 14, 185

10. Jie Chen, Jiongjiong Li, Fu Hu, Qin Zou, Quanjing Mei, Shujun Li, Yulin Hao, Wentao Hou, Jidong Li, Yubao Li, Yi Zuo*, Effect of Microarc Oxidation-treated Ti6Al4V Scaffold Following Low-intensity Pulsed Ultrasound Stimulation on Osteogenic Cells in Vitro, ACS Biomaterials Science & Engineering, 2019, 5: 572-581

10. Fuhua Sun, Jie Chen, Shue Jin, Jian Wang, Yi Man, Jidong Li, Qin Zou, Yubao Li, Yi Zuo*, Development of biomimetic trilayer fibrous membranes for guided bone regeneration, Journal of Materials Chemistry B,2019, 7, 665-675 

11. Wei Fang, Fuhua Sun, Jiajing Tang, Qing Zhao, Jie Chen, Xiaoyu Lei, Jinzheng Zhang, Yinglong Zhang, Yi Zuo*, Jidong Li, and Yubao Li*, Porous electroactive and biodegradable polyurethane membrane through self-doping organogel, Macromolecular Rapid Communications, 2021, Vol. 42, No.12, 2100125

12. Xiaoyu Lei#, Jian Wang#, Jie Chen, Jing Gao, Jinzheng Zhang, Qing Zhao, Jiajing Tang, Wei Fang, Jidong Li, Yubao Li and Yi Zuo*, In vitro evaluation of antibacterial efficacy optimized with cellular apoptosis on multi-functional polyurethane sealers for root canal treatment, Journal of Materials Chemistry B, 2021, Vol. 9, No. 5: 1370-1384