严雪婷 特聘副研究员
通讯地址:成都市望江路29号四川大学分析测试中心239室
电 话:028-85412398(Lab)
E-mail: xtyan@scu.edu.cn
教育及工作经历:
2022.07-至今 四川大学分析测试中心 特聘副研究员
2018.06-2022.07 中国科学院生态环境研究中心,环境化学与生态毒理学国家重点实验室,助理研究员
2019.08-2022.06 香港大学,化学系,博士后
2011.09-2018.06 中国科学院生态环境研究中心,环境化学与生态毒理学国家重点实验室,环境科学,博士
2007.09-2011.06 山西大学,环境与资源学院,环境科学,学士
主要研究领域/方向:
环境毒理学、蛋白质组学、污染物分析与生物毒性领域的相关研究工作
承担科研项目:
2020.01-2022.12 国家自然科学基金青年科学基金项目,21906179,26万,在研,主持。
2020.11-2024.11 国家重点研发计划,2020YFA0907502,子课题,58万,在研,主持。
2021.12-2022.06 香港创新及科技基金,ITS/278/20,20万HK,结题,主持。
代表性科研成果(论文、专利):
1. X. Yan, Q. Yang, X. Fang, P Xiong, S. Liu, Z. Cao, C. Liao*, G. Jiang. Co(II)-based metal–organic framework induced apoptosis through kindling the HIF-1α/BNIP3 signaling pathway in microglial cells. Environ. Sci-Nano, 2021, 8, 2866-2882.
2. X Yan, B. He*, L. Hu*, J. Gao, S. Chen, G. Jiang. Insight into the endocrine disrupting effect and cell response to butyltin compounds in H295R cell: Evaluated with proteomics and bioinformatics analysis. Sci. Total Environ., 2018, 628-629, 1489-1496.
3. X Yan, B. He*, L. Liu, G. Qu, J. Shi, C. Liao, L. Hu*, G. Jiang. Organotin exposure stimulates steroidogenesis in H295R cell via cAMP pathway. Ecotox. Environ. Safe., 2018, 156, 148-153.
4. X. Yan, B. He*, D. Wang, L. Hu*, L. Liu, C. Liao, G. Jiang. Two-dimensional (weak anion exchange chromatography-gel electrophoresis) separations coupling to inductively coupled plasma mass spectrometry strategy for analysis of metalloproteins. Talanta, 2018, 184, 404-410.
5. X. Yan, B. He*, L. Liu, G. Qu, J. Shi, L. Hu*, G. Jiang. Antibacterial Mechanism of Silver Nanoparticles in Pseudomonas aeruginosa: Proteomics approach. Metallomics, 2018, 10, 557-564.
6. X. Yan, Y. Zhou, G. Jiang, H. Li, H. Sun*. “Metallomics and metalloproteomics” in Comprehensive Inorganic Chemistry III (Editor: Vincent P., Guo Z.J.). Elsevier, 2021.
7. S. Deng, X. Yan, P. Xiong, G. Li, T. Ku, N. Liu, C. Liao*, G. Jiang. Nanoscale cobalt-based metal-organic framework impairs learning and memory ability without noticeable general toxicity: First in vivo evidence. Sci. Total Environ., 2021, 771, 145063.
8. P. Xiong, X. Yan, Q. Zhu, G. Qu, J. Shi, C. Liao*, G. Jiang. A review of environmental occurrence, fate, and toxicity of novel brominated flame retardants. Environ. Sci. Technol., 2019, 53, 13551-13569.
9. S. Deng, X.Yan, Q. Zhu, C. Liao*. The utilization of reclaimed water: Possible risks arising from waterborne contaminants. Environ. Pollut., 2019, 254 (Pt A), 113020
10. B. Chen1, L. Fang1, X. Yan, A. Zhang, P. Chen, T. Luan, L. Hu*, G. Jiang. A unique Pb-binding flagellin as an effective remediation tool for Pb contamination in aquatic environment. J. Hazard. Mater., 2019, 363, 34-40.
专利:
1. L. Hu, X. Yan, B. Chen, L. Fang, B. He, G. Jiang. Pb-binding protein flagellin, flagellin encoding gene and application. 香港专利号KH1255720, 已授权
2. 胡立刚,严雪婷,陈保卫,方临川,何滨,江桂斌;铅结合蛋白基因、包含其的蛋白及其应用;专利号201810018214.X,已授权