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张利

发布时间:2019/05/20 浏览量: 来源:

张利

研究员/博士生导师

 

通讯地址:成都市武侯区望江路29号 610064

Tel: 028-85411552

E-mail: zhangli9111@126.com;nic1976@scu.edu.cn

 

教育工作经历

1996—2000年, 四川大学材料学院无机非金属材料专业,工学学士

2000—2005年, 四川大学生物医学工程专业,工学博士

2005—2007年, 四川大学分析测试中心/纳米生物材料研究中心,讲师

2007—2014年,四川大学分析测试中心/纳米生物材料研究中心,副研究员

2014年至今,四川大学分析测试中心/纳米生物材料研究中心,研究员

2016—2017年,加拿大多伦多大学生物材料与生物医学工程研究所,访问学者

 

研究方向:

生物材料;功能材料

 

招生专业

1. 材料学

2. 生物医学工程

主要研究成果:

主要从事生物医用材料的设计及制备、微观结构表征、结构与性能关系、体内外生物学性能评价等研究工作。作为项目负责人先后主持了国家973课题、国家863重点项目、国家自然科学基金青年基金及面上项目等。参与编撰英文专著《Medical Advancements in Aging and Regenerative Technologies: Clinical Tools and Applications》一部,在ACS Nano、ACS Applied Materials & Interfaces、Composite Science and Technology等国内外知名学术期刊发表论文120余篇;申请国家发明专利25项,授权18项。

 

承担科研项目

1. 具有模量匹配和抗菌性能的牙种植体纳米复合材料体系构建及骨整合机理研究. 国家自然科学基金面上项目(No.51673131),73.2万元,2017.1-2020.12,负责人:张利

2. 牙种植体表面低模量纳米材料涂层基础研究,国家973项目(No.2012CB933902),314.69万元,2012.1-2016.12,负责人:张利

3. 三明治型人工皮肤的自剥离设计及中间层的温敏机理研究,国家自然基金青年项目(No.50903052),20万,2010.1-2012.12,负责人:张利

4. 基于纳米复合技术的口腔引导组织再生膜和颌骨修复材料,国家863计划(No.2007AA03Z328766),子课题单位: 60万,2008.1- 2010.12,子课题负责人:张利

 

代表论文(* 通讯作者)

1. Yi Hou, Ying Song, Xiaodong Sun, Yulin Jiang, Meiling He, Yubao Li, Xianchun Chen*,Li Zhang*. Multifunctional Composite Hydrogel Bolus with Combined SelfHealing, Antibacterial and Adhesive Functions for Radiotherapy.Journal of Materials Chemistry.2020, 8:2627-2635

2. Yulin Jiang, Yutao Yang, Xiaoyang Zheng, Yong Yi, Xianchun Chen, Yubao Li, Dan Sun*, Li Zhang*. Multifunctional load-bearing hybrid hydrogel with combined drug release and photothermal conversion functions.NPG Asia Materials.2020, 12:18-28

3. Yi Hou, Nan Jiang, Dan Sun*, Yiping Wang, Xianchun Chen, Songsong Zhu*,Li Zhang*. A fast UV-curable PU-PAAm hydrogel with mechanical flexibility and self-adhesion for wound healing.RSC Advances,2020, 10:4907-4915

4. Bianyun Cai, Nan Jiang, Peijie Tan, Yi Hou, Yubao Li*,Li Zhang*, Songsong Zhu*. The custom making of hierarchical micro/nanoscaled titanium phosphate coatings and their formation mechanism analysis.RSC Advances. 2019, 9: 41311

5. Zhijun Guo, Nan Jiang, Jessica Moore, Colin P. McCoy, Monika Ziminska, Cormac Rafferty, Gianluca Sarri, Andrew R. Hamilton, Yubao Li,Li Zhang, Songsong Zhu and Dan Sun. Nanoscale Hybrid Coating Enables Multifunctional Tissue Scaffold for Potential Multimodal Therapeutic Applications.ACS Applied Materials & Interfaces.2019, 11: 27269-27278

6. Daye Sun, James McLaughlan,Li Zhang, Brian G. Falzon, Davide Mariotti, Paul Maguire, and Dan Sun. Atmospheric Pressure Plasma-Synthesized Gold Nanoparticle/Carbon Nanotube Hybrids for Photothermal Conversion.Langmuir.2019, 35: 4577-4588

7. Birol Ay, Vanessa C. Mendes,Li Zhang, John E. Davies. A“best fit”approach for synergistic surface parameters to guide the design of candidate implant surfaces.Journal of Biomedical Materials Research Part B.2019, 107B: 2165–2177

8. Nan Jiang, Zhijun Guo, Dan Sun, Birol Ay, Yubao Li, Yutao Yang, Peijie Tan,Li Zhang*, Songsong Zhu*. Exploring the mechanism behind improved osteointegration of phosphorylated titanium implants with hierarchically structured topography.Colloids and Surfaces B: Biointerfaces.2019, 184: 110520

9. Miaomiao He, Xianchun Chen, Zhijun Guo, Xiaotao Qiu, Yutao Yang, Chengli Su, Nan Jiang, Yubao Li, Dan Sun*,Li Zhang*. Super tough graphene oxide reinforced polytheretherketone for potential hard tissue repair applications.Composites Science and Technology.2019, 174: 194-201

10. Miaomiao He, Yi Hou, Yulin Jiang, Yubao Li, Qin Zou,Li Zhang*, Weizhong Yang*. Quaternization on polyetheretherketone and its antimicrobial activity.Materials Letters.2019, 235: 242-245

11. Yulin Jiang, Yi Deng, Ying Tu, Birol Ay, Xiaodogn Sun, Yubao Li, Xiaohong Wang, Xianchun Chen*,Li Zhang*. Chitosan-based asymmetric topological membranes with cell-like features for healthcare applications.Journal of Materials Chemistry B.2019, 7: 2634-2641

12. Yi Deng, Min Huang, Dan Sun, Yi Hou, Yubao Li, Taosheng Dong, Xiaohong Wang,Li Zhang*, Weizhong Yang. Dual physically crosslinked k-carrageenan-based double network hydrogels with superior self-healing performance for biomedical application.ACS Applied Materials & Interfaces.2018, 10(43): 37544-37554

13. Nan Jiang, Zhijun Guo, Dan Sun, Yubao Li, Yutao Yang, Chen Chen,Li Zhang* and Songsong Zhu*.PromotingOsseointegration of TiImplants throughMicro/nano-scaledHierarchical TiPhosphate / TiOxideHybridCoating.ACS Nano.2018,12: 7883-7891

14. Xin Lai,Dan Sun,Yi Hou, Yi Zuo, Yubao Li andLi Zhang*. Amino-functionalized multi-layer core-shell mesoporous organosilica nanospheres for Cr(VI) removal.Advanced Materials Interfaces.2018,5:1800630

15. Chen Chen, Xiaodong Sun, Wu Pan, Yi Hou, Rui Liu, Xin Jiang andLi Zhang*. Graphene Oxide-Templated Synthesis of Hydroxyapatite Nanowhiskers To Improve the Mechanical and Osteoblastic Performance of Poly(lactic acid) for Bone Tissue Regeneration.ACS Sustaintable Chemistry & Engineering.2018,6:3862-3869

16. Xin Ren, Chen Chen, Yi Hou, Min Huang, Yubao Li, Danqing Wang* andLi Zhang*. Biodegradable chitosan-based composites with dual functions acting as the bone scaffold and the inflammation inhibitor in the treatment of bone defects.International Jounal of Polymeric Materials and Polymeric Biomaterials.2018, 67(12): 703-710

17. Lincui Da, Mei Gong, Anjing Chen, Yi Zhang, Yizhou Huang, Zhijun Guo, Shengfu Li, Jesse Li-Ling,Li Zhang, Huiqi Xie. Composite elastomeric polyurethane scaffolds incorporating small intestinal submucosa for soft tissue engineering.Acta Biomaterialia.2017, 59: 45–57

18. Min Huang, Yi Hou, Yubao Li, Danqing Wang*,Li Zhang*. High performances of dual network PVA hydrogel modified by PVP using borax as the structureforming.Designed Monomers and Polymers.2017, 20(1): 505-513

19. Hou Yi, Jiang Nan,Zhang Li*, Li Yubao, Meng Yuezhong, Han Dongmei, Chen Chen, Yang Yuan and Zhu Songsong. Oppositely charged polyurethane microspheres with tunable Zeta potentials as an injectable dual-loaded system for bone repair.ACS Applied Materials & Interfaces. 2017, 9: 25808-25817

20. Zhijun Guo, Nan Jiang, Chen Chen, Songsong Zhu,Li Zhang* and Yubao Li. Surface bioactivation through the nanostructured layer on titanium modified by facile HPT treatment.Scientific Report.2017, 7:4155

21. Ying Tu, Chen Chen, Yubao Li, Yi Hou, Min Huang and Li Zhang*. Fabrication of nano-hydroxyapatite/chitosan membrane with asymmetric structure and its applications in guided bone regeneration.Bio-Medical Materials and Engineering.2017, 28:223-233

22. 赖欣,侯毅,李玉宝,黄敏,任欣,张利*.阴阳离子聚氨酯/羟基磷灰石复合微球的制备及其自组装.无机化学学报.2017, 33(8):1403-1410

23. Yi Hou, Chen Chen, Song Zhou, Yubao Li, Danqing Wang*,Li Zhang*. Fabrication of an integrated cartilage/bone joint prosthesis and its potential application in joint replacement.Journal of the Mechanical Behavior of Biomedical Materials. 2016, 59: 265-271

24. Ying Tu, Mingbing Zhou, Zhijun Guo, Yubao Li, Yi Hou, Danqing Wang,Li Zhang*. Preparation and characterization of thermosensitive artificial skin with a Sanwich structure.Materials Letters.2015, 147: 4-7

25. Yi Hou, Chen Chen, Kemin Liu, Ying Tu,Li Zhang* and Yubao Li. Preparation of PVA hydrogel with high-transparence and investigations of its transparent mechanism.RSC Advances.2015, 5: 24023-24030

26. Chen Chen, Ben-Xiang He, Shan-Ling Wang, Gui-Ping Yuan, Li Zhang*. Unexpected observation of highly thermostable transcrystallinity of poly(lactic acid) induced by aligned carbon nanotubes. European Polymer Journal. 2015, 63: 177-185

27. Zhijun Guo, Chen Chen, Qin Gao, Yubao Li, Li Zhang*. Fabrication of silver-incorporated TiO2 nanotubes and evaluation on its antibacterial activity. Materials Letters. 2014, 137:464-467

28. 龚梅,张利*,黄棣,杜晶晶,周名兵,李玉宝,解慧琪.聚氨酯微球的接枝改性及温敏特性.高等学校化学学报2014, 8: 1843-1848

29. "Heart Valve Diseases in Elderly. Current Treatments and Future Directions" of the book“Medical Advancements in Aging and Regenerative Technologies: Clinical Tools and Applications.” Edited byAndriani Daskalaki. Publisher: Idea Group, U.S., ISBN 13: 9781466625068 ISBN 10: 1466625066, 2012.11.30

30. 郭志君,胡盼,王立军,周斌,李玉宝,张利*.载银二氧化钛纳米管表面pH敏感膜构建及其抑菌特性.无机化学学报.2014,30(6):1299-1304

31. 郭志君,周斌,高琴,王立军,胡盼,李玉宝,张利*.阳极氧化工艺参数对TiO2纳米管阵列形貌及性能的影响.功能材料2014, 45(6):6111-6115

32. 郭志君,邹琴,王立军,周斌,李玉宝,张利*.钛表面聚氨酯涂层的生物矿化及其细胞生物学响应.复合材料学报2014, 31(6):1612-1617

33. Song Zhou, Yu-bao Li, Yan-ying Wang, Yi Zuo, Shi-bao Gao,Li Zhang*. Injection-molded porous hydroxyapatite/polyamide-66 scaffold for bone repair and investigations on the experimental conditions.Polymer Engineering and Science.2014, 54:1003-1012

34. Song Zhou, Yu-bao Li, Yos S. Morsi, Yan-ying Wang, Chen Chen, Li Zhang*. Effects of ethylene-vinyl acetate copolymer on the morphology and mechanical properties of hydroxyapatite/polyamide 66 composites for bone tissue engineering.Polymer-Plastics technology and engineering.2014, 53: 290-297

35. Yi Deng, Peizhi Zhu,Li Zhang*, and Shicheng Wei. In Vitro growth of bioactive nanostructured apatites via agar-gelatin hybrid hydrogel.Journal of Biomedical Nanotechnology.2013, 9: 1972-1983

36. Yi Deng, Huanan Wang,Li Zhang*, Yubao Li, Shicheng Wei. In situ synthesis and in vitro biocompatibility of needly-like nano-hydroxyapatite in agar-geltin co-hydrogel.Materials Letters.2013, 104:8-12

37. Li Zhang, Yosry Morsi, Yanying Wang, Yubao Li, Seeram Ramaknshna. Review scaffold design and stem cells for tooth regeneration.Japanese Dental Science Review.2013, 49(1):14-26